TY - BOOK AU - Sauna,Zuben E. AU - Kimchi-Sarfaty,Chava ED - SpringerLink (Online service) TI - Protein Therapeutics T2 - Topics in Medicinal Chemistry, SN - 9783319418186 AV - RS400-431 U1 - 615.19 23 PY - 2017/// CY - Cham PB - Springer International Publishing, Imprint: Springer KW - Medicinal chemistry KW - Biomedical engineering KW - Proteins  KW - Medicinal Chemistry KW - Biomedical Engineering and Bioengineering KW - Protein Science N1 - Protein Production in Eukaryotic Cells -- Production of Protein Therapeutics in the Quality by Design (QbD) Paradigm -- Characterization of Therapeutic Proteins -- Immunogenicity Lessons Learned from the Clinical Development of Vatreptacog Alfa, A Recombinant Activated Factor VII Analog, in Hemophilia with Inhibitors -- The Art of Gene Redesign and Recombinant Protein Production: Approaches and Perspectives; Available to subscribing member institutions only. Доступно лише організаціям членам підписки N2 - Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors UR - https://doi.org/10.1007/978-3-319-41818-6 ER -