TY  - BOOK
AU  - Brekken,Rolf A.
AU  - Stupack,Dwayne
ED  - SpringerLink (Online service)
TI  - Extracellular Matrix in Tumor Biology
T2  - Biology of Extracellular Matrix,
SN  - 9783319609072
AV  - RC261-271 
U1  - 614.5999 23
PY  - 2017///
CY  - Cham
PB  - Springer International Publishing, Imprint: Springer
KW  - Cancer research
KW  - Immunology
KW  - Molecular biology
KW  - Oncology  
KW  - Proteins 
KW  - Cell biology
KW  - Cancer Research
KW  - Molecular Medicine
KW  - Oncology
KW  - Receptors
KW  - Cell Biology
N1  - 1. The extracellular matrix of tumors: a focus on fibronectin and fibulin-5 -- 2. Internalization of collagen: an important matrix turnover pathway in cancer -- 3. Lumican, a Small Leucine-Rich Proteoglycan, and Its Biological Function in Tumor Progression  -- 4. Versican: Role in Cancer Tumorigenesis -- 5. Engineering advanced models of the glioblastoma microenvironment using biomaterials -- 6. Breaching and opening basement membrane barriers: the anchor cell leads the way; Available to subscribing member institutions only. Доступно лише організаціям членам підписки
N2  - This volume provides an overview on the influence of Extracellular Matrix (ECM) on tumor progression. It covers topics such as signaling induced by structural ECM proteins including collagen and fibronectin, the control of ECM deposition and the turnover in tumors. Also discussed are the migration of cells through basement membranes and the function of proteoglycans including lumican and veriscan in tumor progression. Biomaterial-based in-vitro models as well as C. elegans models of the tumor microenvironment are used to show how these models can lead to a greater understanding of the disease mechanisms that promote cancer progression. The book addresses researchers working on cancer biology or ECM, and oncologists alike
UR  - https://doi.org/10.1007/978-3-319-60907-2
ER  -