TY - BOOK AU - Müller,Werner E.G. AU - Schröder,Heinz C. AU - Wang,Xiaohong ED - SpringerLink (Online service) TI - Blue Biotechnology: From Gene to Bioactive Product T2 - Marine Molecular Biotechnology, SN - 9783319512846 AV - QP501-801 U1 - 573.44 23 PY - 2017/// CY - Cham PB - Springer International Publishing, Imprint: Springer KW - Biochemistry KW - Cell biology KW - Pharmacology KW - Biotechnology KW - Molecular biology KW - Animal genetics KW - Animal Biochemistry KW - Cell Biology KW - Pharmacology/Toxicology KW - Molecular Medicine KW - Animal Genetics and Genomics N1 - 35 Years of Marine Natural Product Research in Sweden: Cool Molecules and Models from Cold Waters -- Major Antimicrobial Representatives from Marine Sponges and/or Their Associated Bacteria -- Discovery and Development of Novel Drugs -- Computer Aided Drug Discovery from Marine Compounds: Identification of the Three-dimensional Structural Features Responsible for Antimalarial Activity -- BlueGenics: Bioactive Natural Products of Medicinal Relevance and Approaches to Their Diversification -- New Target Sites for Treatment of Osteoporosis -- Biocalcite and Carbonic Acid Activators -- Electrospinning of Bioactive Wound Healing Nets -- Entotheonella Bacteria as Source of Sponge-derived Natural Products: Opportunities for Biotechnological Production; Available to subscribing member institutions only. Доступно лише організаціям членам підписки N2 - This book describes the discovery of molecules from unexploited extreme marine environments, and presents new approaches in marine genomics. It combines the current state of knowledge in marine genomics and advanced natural products’ chemistry to pursue the sustainable production of novel secondary metabolites (lead compounds), as well as pharmacologically active peptides/proteins, with antimicrobial, neuroprotective, anti-osteoporotic, anti-protozoan/anti-plasmodial, anti-ageing and immune-modulating effects. Further, it employs molecular-biology-based approaches and advanced chemical techniques to obtain and to select candidate compounds for pre-clinical and clinical studies UR - https://doi.org/10.1007/978-3-319-51284-6 ER -