TY - BOOK AU - Agotegaray,Mariela A. AU - Lassalle,Verónica L. ED - SpringerLink (Online service) TI - Silica-coated Magnetic Nanoparticles: An Insight into Targeted Drug Delivery and Toxicology T2 - SpringerBriefs in Molecular Science, SN - 9783319501581 AV - T174.7 U1 - 620.115 23 PY - 2017/// CY - Cham PB - Springer International Publishing, Imprint: Springer KW - Nanotechnology KW - Nanochemistry KW - Pharmacology KW - Pharmacology/Toxicology N1 - Chapter 1: Introduction -- Chapter 2: Chemistry overview -- Chapter 3: Biological features -- Chapter 4: Toxicological insights -- Chapter 5: Overview on applications for the treatment of specific diseases -- Chapter 6: New insights on silica-coated magnetic nanoparticles; Available to subscribing member institutions only. Доступно лише організаціям членам підписки N2 - This brief offers a comprehensive discussion of magnetic targeted drug delivery of silica-coated nanodevices. Focusing on the latest trend in pharmaceutical applications of these nanodevices, a multidisciplinary overview is displayed, from synthesis and design to pharmacokenetics, biodistribution and toxicology. Chapters include design of silica-coated magnetic nanodevices; techniques for drug loading with features applicable to biological systems; synthesis, characterization and the assessment of biomedical issues with both in vitro and in vivo experiments. Applications in the treatment of different localized diseases are also addressed in order to present the potential use of these nanosystems as global, commercially available therapeutics UR - https://doi.org/10.1007/978-3-319-50158-1 ER -