TY - BOOK AU - Nikolaev,Viacheslav AU - Zaccolo,Manuela ED - SpringerLink (Online service) TI - Microdomains in the Cardiovascular System T2 - Cardiac and Vascular Biology, SN - 9783319545790 AV - R856-R857 U1 - 610.28 23 PY - 2017/// CY - Cham PB - Springer International Publishing, Imprint: Springer KW - Biomedical engineering KW - Cardiovascular system KW - Computer simulation KW - Cardiology KW - Biomedical Engineering/Biotechnology KW - Cardiovascular Biology KW - Simulation and Modeling N1 - Available to subscribing member institutions only. Доступно лише організаціям членам підписки N2 - The book comprehensively presents new findings in cardiovascular research related to signaling microdomains in health and disease. Important second messengers such as cAMP, cGMP, calcium and their role in microdomain signaling are discussed. The book offers and explains methodical approaches and technical ways how to successfully analyze microdomain signaling, also in the context of disease. It further provides scientific perspectives and strategies that are based on the concept of signaling within microdomains and that can revolutionize pharmacology and eventually lead to the effective treatment of cardiovascular diseases in future. This book is written for scientists in cardiovascular research, pharmacology, molecular and cellular biology as well as medical doctors in cardiology, angiology and nephrology.  UR - https://doi.org/10.1007/978-3-319-54579-0 ER -