Biomedical Materials Science is dedicated to the advancement of biomaterials science, with a primary focus on the application and use of biomedical materials in medicine and healthcare. The journal aims to publish high-quality research articles, reviews, and communications that not only advance the science and innovation of biomaterials, but also emphasize their real-world usability and clinical relevance, ensuring that each material's potential is evaluated through the lens of practical healthcare application. The scope of the journal includes, but is not limited to, the following areas: Application of biomaterials in various clinical settings, including surgical implants, wound healing, and a wide range of other therapeutic interventions Biomaterials science focusing on the molecular and cellular interactions between biomaterials and biological systems, their bioactivity, biocompatibility, and biosafety, mechanistic aspects, pathways, and particularly in promoting healing and regeneration of tissues Biomaterials design, development and properties, including the engineering and functionalization of materials with complex structures and functions, scaffolds and hydrogels for tissue engineering and regenerative medicine. The focus is on studies that are able not only to drive material innovation but also to prioritize clinical usability and real-world healthcare application. This area includes the exploration of nanomaterials and nanotechnology for medical applications, including diagnostics and therapeutics Innovations and advancements in bioprinting technologies for a broad range of applications, from complex tissue engineering and regenerative medicine, biohybrid devices, cancer research, vascularization studies, to drug testing and personalized medicine. Bio-based textiles and wearables Biomaterials for Drug Delivery Technologies and controlled release systems, enhancing the efficacy and targeting of therapeutics Biomaterials for tissue engineering and regeneration Biomedical Materials Science serves as a platform for researchers, clinicians, and industry professionals to share their findings and innovations, fostering collaboration and advancing the field of biomaterials. The journal welcomes submissions that provide significant insights and advancements in the design, development, and application of biomaterials for improving human health. Study Types and Requirements Biomedical Materials Science welcomes submissions employing in vitro, ex vivo, in vivo, and comprehensive physico-chemical or mechanical characterization approaches. Authors should follow the guidelines below: 1. In Vitro Studies 1.1 Accepted when they provide robust mechanistic insights (e.g., multi-omics, cell–material interactions). 1.2 Advanced models such as organoids, organ-on-chip systems, engineered tissues, and other complex platforms are strongly encouraged and considered valid alternatives to animal testing. 1.3 Conventional cell culture alone is generally insufficient for regenerative medicine applications unless supported by comprehensive and well-contextualized datasets. 2. In Vivo Data 2.1 Required when the biomaterial is intended for near-term clinical or in vivo application. 2.2 Not mandatory for studies focused on method development, early-stage mechanistic research, or exploratory technologies. 3. Ex Vivo Studies 3.1 Acceptable when data are rigorous, convincing, and appropriately contextualized, especially when in vivo testing is impractical or not ethically justified. 3.2 Should provide meaningful insights into performance relevant to the intended biological or clinical application. 4. Physico-Chemical and Mechanical Characterization Studies 4.1 Comprehensive characterization studies may be considered when they provide a multi-dimensional, rigorous evaluation of the material’s properties and relevance to biomedical applications. 4.2 Studies based solely on minimal or incremental physico-chemical or mechanical testing are not sufficient. 4.3 Suitable studies should clearly demonstrate novelty, rigor, and relevance to biomedical materials science, contributing meaningfully to material design, performance prediction, or translational pathways. 5. Ethical and Field Considerations 5.1 The journal supports the reduction of animal testing and encourages advanced alternative models where appropriate. 5.2 Titles, claims, and conclusions must accurately reflect the strength and scope of the presented data.