Modelling the Toxicity of Nanoparticles [electronic resource] / edited by Lang Tran, Miguel A. Bañares, Robert Rallo.

Інтелектуальна відповідальність: Вид матеріалу: Текст Серія: Advances in Experimental Medicine and Biology ; 947Публікація: Cham : Springer International Publishing : Imprint: Springer, 2017Видання: 1st ed. 2017Опис: XVII, 352 p. 102 illus., 83 illus. in color. online resourceТип вмісту:
  • text
Тип засобу:
  • computer
Тип носія:
  • online resource
ISBN:
  • 9783319477541
Тематика(и): Додаткові фізичні формати: Printed edition:: Немає назви; Printed edition:: Немає назви; Printed edition:: Немає назвиДесяткова класифікація Дьюї:
  • 615 23
Класифікація Бібліотеки Конгресу:
  • RM1-950
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Вміст:
Engineered Nanoparticles – Their physico-chemical characteristics and how to measure them -- Measurement -- The Life-Cycle of Engineered Nanoparticles -- From Dose to Response – In vivo Nanoparticle Processing and Potential Toxicity -- From Dose to Response – Literature review od (Q)SAR Modelling of Nanomaterial Toxicity -- Systems biology to support nanomaterial grouping -- Multiscale modelling of bionano interface -- Biological Surface Adsorption Index of Nanomaterials - Modeling Surface Interactions of Nanomaterials with Biomolecules -- Case study I - An integrated data-driven strategy for safe-by-design nanoparticles: The FP7 MODERN Project -- Case study II - Compilation of Data and Modeling of Nanoparticle Interactions and Toxicity and in the European NanoPUZZLES Project -- Case study III – The construction of a nanotoxicity database: the MOD-ENP-TOX experience.
У: Springer eBooksЗведення: In today’s nanotechnology and pharmaceutical research, alternative toxicology testing methods are crucial for ethically and commercially sound practice. This book provides practical guidelines on how to develop and validate quantitative nanostructure-toxicity relationship (QNTR) models, which are ideal for rapidly exploring the effects of a large number of variables in complex scenarios. Through contributions by academic, industrial, and governmental experts, Modelling the Toxicity of Nanoparticles delivers clear instruction on these methods and their integration and use in risk assessment. Specific topics include the physico-chemical characteristics of engineered nanoparticles, nanoparticle interactions, in vivo nanoparticle processing, and more. A much-needed practical guide, Modelling the Toxicity of Nanoparticles is a key text for researchers as well as government and industry regulators.
Тип одиниці: ЕКнига Списки з цим бібзаписом: Springer Ebooks (till 2020 - Open Access)+(2017 Network Access)) | Springer Ebooks (2017 Network Access))
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Engineered Nanoparticles – Their physico-chemical characteristics and how to measure them -- Measurement -- The Life-Cycle of Engineered Nanoparticles -- From Dose to Response – In vivo Nanoparticle Processing and Potential Toxicity -- From Dose to Response – Literature review od (Q)SAR Modelling of Nanomaterial Toxicity -- Systems biology to support nanomaterial grouping -- Multiscale modelling of bionano interface -- Biological Surface Adsorption Index of Nanomaterials - Modeling Surface Interactions of Nanomaterials with Biomolecules -- Case study I - An integrated data-driven strategy for safe-by-design nanoparticles: The FP7 MODERN Project -- Case study II - Compilation of Data and Modeling of Nanoparticle Interactions and Toxicity and in the European NanoPUZZLES Project -- Case study III – The construction of a nanotoxicity database: the MOD-ENP-TOX experience.

In today’s nanotechnology and pharmaceutical research, alternative toxicology testing methods are crucial for ethically and commercially sound practice. This book provides practical guidelines on how to develop and validate quantitative nanostructure-toxicity relationship (QNTR) models, which are ideal for rapidly exploring the effects of a large number of variables in complex scenarios. Through contributions by academic, industrial, and governmental experts, Modelling the Toxicity of Nanoparticles delivers clear instruction on these methods and their integration and use in risk assessment. Specific topics include the physico-chemical characteristics of engineered nanoparticles, nanoparticle interactions, in vivo nanoparticle processing, and more. A much-needed practical guide, Modelling the Toxicity of Nanoparticles is a key text for researchers as well as government and industry regulators.

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