Applications of Mathematics publishes original research papers of high scientific level that are directed towards the use of mathematics in different branches of science. The emphasis of the papers is on a solid mathematical analysis of problems from applications, in the form of proofs of mathematical theorems that are typically of more general use than only for the application under consideration. The journal publishes theorems on solutions to (partial) differential, integral, algebraic and stochastic equations, such as their well-posedness, their relevant properties, and their (numerical) approximation. Also papers on variational (in-)equalities, optimization and probability and statistics are welcomed. All contributions should be well motivated by real-life applications from scientific areas such as engineering, physics, econometrics, and biology.