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- After years of work as a small town doctor and a research scientist, Arrowsmith heads for the West Indies with a serum to halt an epidemic. A tragic turn of events forces him to come to terms with his career and his personal life
- Businessmen
- City and town life
- Clergy
- Conformity
- Evangelists
- Fiction
- Lewis, Sinclair
- Married women
- Medicine in literature
- Medicine in Literature
- Middle-aged men
- Middle class men
- Minnesota
- Protestant churches
- Real estate agents
- Satirical fiction, American
- Small town life
- The Twenties (20th century)
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