GeroScience is a bi-monthly, international, peer-reviewed journal that publishes articles related to research in the biology of aging, pathophysiology of age-related diseases and research on biomedical applications that impact aging and/or the pathogenesis of diseases associated with old age. The scope of articles to be considered covers the whole spectrum of Geroscience and include physiology/pathophysiology, geriatrics/gerontology, neuroscience, biochemistry, pathology, molecular and cell biology, biophysics, genetics, genomics, proteomics, epigenetics and relevant sub-fields of endocrinology, immunology, pharmacology, neurology, cardiovascular medicine, ophthalmology, nursing, otolaryngology and psychology. GeroScience is especially interested in manuscripts developing innovative pharmacological, genetic or nutritional strategies to improve cardiovascular, neurocognitive, and musculoskeletal health-span. It welcomes studies using a variety of experimental approaches, including in vivo studies and investigations using isolated tissue preparations and cultured cells. Articles focusing on the intersection of aging research, nutritional sciences and alternative and complementary medicine are considered. Articles concerning veterinary sciences (e.g. studies on age-related pathologies of companion dogs, horses and non-human primates), comparative biology and evolutionary biology are also encouraged. Articles concerning clinical investigations are also considered especially if the results reveal the underlying biological mechanisms of aging (e.g. the role of inflammation, senescence or oxidative stress in the pathogenesis of age-related diseases). Studies must reflect more than issues related to the care and treatment of geriatric patients. Papers concerned with social, economic, and political issues of aging will generally not be considered unless they relate directly to biomedical gerontology. In addition to manuscripts emerging from original research, the journal actively solicits research reviews of important topics in biomedical gerontology. Other types of manuscripts are also acceptable, such as commentaries, debates, and meeting reports.